cFMS Receptor Tyrosine Kinase Inhibitor
     
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cFMS Receptor Tyrosine Kinase Inhibitor

5-Cyano-N-(2,5-di-1-piperidinylphenyl)-2-furancarboxamide

cFMS_Receptor_Tyrosine_Kinase_Inhibitor
OTAVAchemicals Catalogue Number: 7070707032
CAS Registry Number: 959626-45-0
Purity: 97%+ (HPLC)


Ref.: Player et al. Potent 2'-aminoanilide inhibitors of cFMS as potential anti-inflammatory agents. Bioorganic & Medicinal Chemistry Letters (2007), 17, 6070-6074


Abstract: A series of 2'-aminoanilides have been identified which exhibit potent and selective inhibitory activity against the cFMS tyrosine kinase. Initial SAR studies within this series are described which examine aroyl and amino group substitutions, as well as the introduction of hydrophilic substituents on the benzene core.

 
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