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How to work with SDF files
File Format Description
Chemical data file created in the Structure Data File (SDF) format, which was developed by Molecular Design Limited (MDL); saved in plain text and contains chemical structure records; used as a standard exchange format for chemicals information. Molecular Design Limited was renamed to MDL Information Systems and then later was acquired by Symyx Technologies, the organization that now maintains the SDF format.
Programs that open .SDF files:

MacOS and Linux