Fragment Libraries
     
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Fragment Libraries
General Fragments Library

Supplier stockUPDATED! The library has been just updated!
The central purpose of this specially designed Fragment Library is to provide

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Fluorine Fragment Library

Supplier stockNMR is a powerful means for implementing FBDD, and several approaches have been proposed utilizing 1H–15N heteronuclear single quantum coherence as well as one-dimensional 1H and 19F NMR to screen compound mixtures against a target of interest.

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Solubility Fragment Library

Solubility Fragment Library

The Solubility Fragment Library consists of about 957 low molecular fragments with "Rule-of-Three" compliance and assured solubility in both DMSO (200mM) and PBS buffer (1mM). The library design included diversity filtering in order to provide chemical structure variety for your fragment screening program.

 

 

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Chelator Fragment Library

Chelator Fragments LibraryFragment-based lead design (FBLD) could be used to identify new metal-binding groups for metalloenzyme inhibitors. Several small-molecule chelators have been shown to effectively inhibit metalloproteins, therefore the design,

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Halogen-Enriched Fragments

Halogen-Enriched Fragment LibraryOur Halogen-Enriched Fragment Library comprises 708 brominated fragments that can explore binding sites for favorable halogen bond interactions to identify unique binding modes that are complementary to those obtained from classical fragment-based screening.
 

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