HDAC, EGFR, and HER2 Inhibitor
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HDAC, EGFR, and HER2 Inhibitor

7-[4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-quinazolin-6-yloxy]-heptanoic acid hydroxyamide

Potent multi-acting HDAC, EGFR, and HER2 inhibitor.

HDAC enzyme assay IC50 = 6.5 nM, EGFR = 3.1 nM, HER2 = 19.0 nM


HDAC, EGFR, and HER2 Inhibitor

OTAVAchemicals Catalogue Number:  7070707144

CAS Registry Number:  1012054-55-5

Purity:  95%+


Ref.: J. Med. Chem. 2010, 53, 2000–2009

Abstract: Potent multiacting HDAC, EGFR and HER2 inhibitor, exhibiting in most tumor cell lines tested efficient antiproliferative activity with greater potency than vorinostat (SAHA), erlotinib, lapatinib, and combinations of vorinostat/erlotinib and vorinostat/lapatinib

DOI: 10.1021/jm901453q


Price info:
1 MG 30 EUR
5 MG 100 EUR
10 MG 150 EUR
300uL of 10mM solution

90 EUR