PI3K

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PI3K


7070707142

Dual PI3K-α and mTOR inhibitor

1-(4-{[4-(dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea (PKI-587, PF-05212384)

OTAVAchemicals Catalogue Number:  7070707142

CAS Registry Number:  1197160-78-3

Purity:  95%+

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7070707058

TGX115

8-(2-Methylphenoxy)-2-(4-morpholinyl)-4(1H)-quinolinone

A potent and selective inhibitor of PI 3-K isoforms p110b/p110e (IC50 p110b=0.13uM, p110e=0.63uM)

OTAVAchemicals Catalogue Number: 7070707058

CAS Registry Number: 351071-62-0

Purity: 97% (HPLC)

 

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7070707046

Inhibitor_of_the_p110_isoform_of_PI3_kinase

2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone

Selective PI3Kdelta inhibitor IC50 = 3.2 µM

Chemical Formula: C22H19N7O

Molecular Weight: 397.4

OTAVAchemicals Catalogue Number: 7070707046

CAS Registry Number: 371242-69-2

Purity: 98% (HPLC)

 

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7070707047

TGX155

8-(4-Fluoro-2-methylphenoxy)-2-(4-morpholinyl)-4(1H)-quinolinone (TGX155)

OTAVAchemicals Catalogue Number: 7070707047

CAS Registry Number: 351071-90-4

Purity: 95%+ (HPLC)

 
7070707028

PIK-90

N-(2,3-Dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide (PIK-90)

• PIK-90 is a potent and cell permeable PI3K inhibitor, with IC50 values of 11 nM, 350 nM, 18 nM, and 58 nM for p110 α, β, γ and δ isoforms

OTAVAchemicals Catalogue Number: 7070707028

CAS Registry Number: 677338-12-4

Purity: 95%+ (HPLC)

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