6-Methyl-4-(3-nitro-phenyl)-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid ethyl ester

calcium channel blocker; induces apoptotic cell death in triple negative breast cancer (TNBC) cells 

Chemical Formula: C14H15N3O5

Molecular Weight: 305.3

OTAVAchemicals Catalogue Number:   0111850003

CAS Registry Number:  110448-29-8

Purity: >95%

N-[(4-Methoxyphenyl)methyl]-1-naphthalenemethanamine hydrochloride

ML 133 hydrochloride is a selective blocker of inwardly rectifying Kir2 potassium channels (IC50 values are 1.8, 2.8, 2.9 and 4.0 µM at pH 7.4 for mKir2.1, hKir2.6, hKir2.2 and hKir2.3 respectively).

Exhibits no effect on rKir1.1 (IC50 > 300 µM); displays weak activity at hKir7.1 and rKir4.1 (IC50 values are 33 and 76 µM)

Chemical Formula: C19H20ClNO

Molecular Weight: 313.8

OTAVAchemicals Catalogue Number: 1869197

CAS Registry Number: 1222781-70-5

Purity: 99% (HPLC)

4-[[4-Oxo-2-thioxo-3-[3-(trifluoromethyl)phenyl]-5-thiazolidinylidene]methyl]-benzoic acid (CFTR_inh-172)

It blocks CFTR-dependent Cl- currents in airway cells with K_I ~ 300 nM, nearly 500-fold more potent than that of the reference CFTR blocker glibenclamide

OTAVAchemicals Catalogue Number: 0129690030

CAS Registry Number: 307510-92-5

Purity: 95%+ (HPLC)