|
N-[2-methyl-5-({[(3,4,5-trimethoxybenzoyl)amino]carbonothioyl}amino)phenyl]biphenyl-4-carboxamide
An inhibitor of the Hh signaling pathway (IC50 = 9 nM)
Chemical Formula: C31H29N3O5S
Molecular Weight: 555.6579
OTAVAchemicals Catalogue Number: 7070707159
CAS Registry Number: 1263132-08-6
Purity: 99% (HPLC)
|
Read more...
|
N-[2-methyl-5-({[(3,4,5-trimethoxybenzoyl)amino]carbonyl}amino)phenyl]biphenyl-4-carboxamide
An inhibitor of the Hh signaling pathway (IC50 = 6 nM)
Chemical Formula: C31H29N3O6
Molecular Weight: 539.5933
OTAVAchemicals Catalogue Number: 7070707158
CAS Registry Number: 1359944-56-1
Purity: 99% (HPLC)
|
Read more...
|

N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]-urea
inhibitor of the Hedgehog Signalling Pathway with IC50 = 70 nM
OTAVAchemicals Catalogue Number: 1156359
CAS Registry Number: 330796-24-2
Purity: 97%+ (HPLC)
|
Read more...
|
N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-thiazolamine
Hedgehog signaling inhibitor that prevents Gli-dependent transcriptional activity (IC50 = 30 nM). Exhibits antiproliferative activity in a range of cancer cell lines (GI50 = 3 - 21 nM)
and in human xenografts in vivo. Inhibits alcohol dehydrogenase 7 (Adh7) (IC50 = 210 nM) and acts as a microtubule depolymerizing agent in vitro
OTAVAchemicals Catalogue Number: 7211760148
CAS Registry Number: 315703-52-7
Purity: 98% (HPLC)
|
Read more...
|
|
|
|
|