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N-allyl-6-bromo-quinazolin-4-amine
mTOR-independent small molecule enhancer of autophagy
Chemical Formula: C11H10BrN3
Molecular Weight: 264.1
OTAVAchemicals Catalogue Number: 7010010139
CAS Registry Number: 307538-42-7
Purity: 98%
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9-(6-Aminopyridin-3-yl)-1-(3-(trifluoromethyl)-phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2)
OTAVAchemicals Catalogue Number: 7070707148
CAS Registry Number: 1223001-51-1
Purity: 95%+ (HPLC)
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2-(4-Morpholinyl)-4H-Pyrimido[2,1-a]isoquinolin-4-one
Reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR) (IC50 values are 0.28 and 5.3 ìM respectively). Displays little affinity for other
commonly studied kinases including PI 3-K, ATM and ATR (IC50 values are all > 100 ìM). Induces apoptosis in vitro
OTAVAchemicals Catalogue Number: 7070707024
CAS Registry Number: 168425-64-7
Purity: 97%+ (HPLC)
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1-(4-{[4-(dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea (PKI-587, PF-05212384)
OTAVAchemicals Catalogue Number: 7070707142
CAS Registry Number: 1197160-78-3
Purity: 95%+
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