PFTA32

3-[(5Z)-5-[[5-(2-fluorophenyl)-2-furyl]methylene]-4-oxo-2-thioxo-thiazolidin-3-yl]propanoic acid

Inhibitor of apoptosis signal-regulating kinase 1 (ASK1), IC₅₀ = 0.3 μM.

OTAVAchemicals Catalogue Number:   7119152011

CAS Registry Number:  N/A

Purity: >95%

PFTA13

4-[(5Z)-5-[[5-(2-chlorophenyl)-2-furyl]methylene]-4-oxo-2-thioxo-thiazolidin-3-yl]butanoic acid

Inhibitor of apoptosis signal-regulating kinase 1 (ASK1), IC₅₀ = 0.3 μM.

OTAVAchemicals Catalogue Number:   7216540395

CAS Registry Number:  N/A

Purity: >95%

PFTA26

4-[(5Z)-5-[[5-(4-bromophenyl)-2-furyl]methylene]-4-oxo-2-thioxo-thiazolidin-3-yl]butanoic acid

Inhibitor of apoptosis signal-regulating kinase 1 (ASK1), IC₅₀ = 0.2 μM.

OTAVAchemicals Catalogue Number:   7216540398

CAS Registry Number:  N/A

Purity: >95%

PFTA25

6-[(5E)-5-[[5-(4-bromophenyl)-2-furyl]methylene]-4-oxo-2-thioxo-thiazolidin-3-yl]hexanoic acid

Inhibitor of apoptosis signal-regulating kinase 1 (ASK1), IC₅₀ = 0.2 μM.

OTAVAchemicals Catalogue Number:   7216540347

CAS Registry Number:  N/A

Purity: >95%

2,7- dioxo-2,7 -dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate

New potent and selective inhibitor of ASK1 with IC₅₀ = 3 μM, K_i=500 nM

OTAVAchemicals Catalogue Number: 7214191049

CAS Registry Number: 175026-96-7

Purity: 95%+ (HPLC)