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E-4-hydroxy-N-4-isopropylbenzylidene benzohydrazide, 4-hydroxy-benzoic acid 4-isopropyl-benzylidene-hydrazide;
2-[[4-(1-Methylethyl)phenyl]methylene]hydrazide 4-hydroxybenzoic acid
GSK 4716 is an Estrogen-related receptors ERRß and ERRa agonist with minimal activity for ERRa, ERa and ERß
Chemical Formula: C17H18N2O2
Molecular Weight: 282.3
OTAVAchemicals Catalogue Number: 0127440673
CAS Registry Number: 101574-65-6
Purity: 98%+ (HPLC)
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N-(3-Methylphenyl)-4-(4-pyridinyl)-2-thiazolamine (STF-62247)
selectively induces cell death in VHL-deficient cells
OTAVAchemicals Catalogue Number: 7211760086
CAS Registry Number: 315702-99-9
Purity: 95%+ (HPLC)
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(±)-cis-2-{[(3,5-dichlorophenyl)amino]carbonyl}cyclohexanecarboxylic acid ((1R,2S)-rel-2-[[(3,5-dichlorophenyl)amino]carbonyl]-cyclohexanecarboxylic acid; VU0155041)
• Positive allosteric selective modulator at mGluR4 (EC50 values are 798 nM and 693 nM at human and rat mGluR4 receptors respectively). It has advantages over PHCCC (Asc-043) as it is water soluble and more potent. Active in behavioural models of Parkinsons Disease
Relative stereochemistry
OTAVAchemicals Catalogue Number: 7114471128
CAS Registry Number: 1093757-42-6
CAS Registry Number: 1259372-69-4 (sodium salt)
Purity: 95%+ (HPLC)
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2-[(Aminoiminomethyl)amino]ethyl carbamimidothioic acid ester (S-(2-guanidylethyl)-isothiourea; VUF 8430 dihydrobromide)
VUF 8430 dihydrobromide is a potent histamine H4 receptor full agonist (pEC50 = 7.3), high affinity (pKi = 7.5)
OTAVAchemicals Catalogue Number: 7070707134
CAS Registry Number: 100130-32-3
CAS Registry Number: 98021-17-1 (free base)
Purity: 97%+
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7-[4-([1,1'-Biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone (Bifeprunox)
a potent dopamine D2-like and 5-HT1A receptor partial agonist with pKis of 7.19 and 8.83 for cortex 5-HT1A and striatum D2, and a pEC50 of 6.37 for hippocampus 5-HT1A, respectively.
Bifeprunox is an antipsychotic for the research of schizophrenia
OTAVAchemicals Catalogue Number: 7070707030
CAS Registry Number: 350992-10-8
Purity: 97%+ (HPLC)
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