As a part of our company’s strategy to deliver the most up-to-date products and services to the global research community, we are offering comprehensive synthetic services to provide a vast array of novel compounds from Synthetically Accessible Virtual Inventory (SAVI) Database [1].

This SAVI project started as an international collaboration to computationally generate an extensive database of reliably synthesized and reasonably priced screening compounds that have desirable properties for the drug development process [2].

Discovery of new pharmaceutical substances could be substantially augmented by utilizing this SAVI library comprising about 283 millions of unexplored chemical compounds which are not present in screening databases [3].

You could select any compounds from this SAVI database [1] and send us a quote request for the syntheses of these new molecules.

If you have any questions or would like more information, our team members will be happy to help.

Please feel free contact us for more details.

References:

1. Synthetically Accessible Virtual Inventory (SAVI) Database: https://cactus.nci.nih.gov/download/savi_download/.
2. Patel H., Pevzner Y., Ihlenfeldt W. D., Nicklaus M. Synthetically Accessible Virtual Inventory (SAVI): Reaction generation and handling at the billion compound scale. 11th International Conference on Chemical Structures. May 27-31 2018, Noordwijkerhout, The Netherlands: http://www.int-conf-chem-structures.org/fileadmin/user_upload/ICCS_2018/lectures/A01-Patel.pdf
3. Pogodin P. V., Lagunin A. A., Rudik A. V., Filimonov D. A., Druzhilovskiy D. S., Nicklaus M. C., Poroikov V. V. (2018) How to Achieve Better Results Using PASS-Based Virtual Screening: Case Study for Kinase Inhibitors. Front. Chem. 2018, Vol. 6:133. doi: 10.3389/fchem.2018.00133

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