3-(4-chlorophenyl)-6-methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol

protein kinase C inhibitor, low-ceiling diuretic drug

Chemical Formula: C14H12ClNO2

Molecular Weight: 261.7

OTAVAchemicals Catalogue Number:  3709336

CAS Registry Number:  89943-82-8

Purity:  95%

7-imidazol-1-yl-5,6-dihydronaphthalene-2-carboxylic acid

Thromboxane-A synthase inhibitor

Chemical Formula: C14H12N2O2

Molecular Weight: 240.3

OTAVAchemicals Catalogue Number:  3703212

CAS Registry Number:  89781-55-5

Purity:  95%

6-fluoro-N-[(4-fluorophenyl)methyl]quinazolin-4-amine

autophagy inhibitor

Chemical Formula: C15H11F2N3

Molecular Weight: 271.3

OTAVAchemicals Catalogue Number:  1736860

CAS Registry Number:  1262888-28-7

Purity:  95%

N-(6-Benzyl-2-phenethylamino-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-yl)-3-chloro-2-methyl-benzenesulfonamide

CaMKII inhibitor

Chemical Formula: C29H30ClN5O2S

Molecular Weight: 548.1

OTAVAchemicals Catalogue Number:  7139318

CAS Registry Number:  1208123-85-6

Purity: >95%

3-Phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-2-propenamide

Cell-permeable, selective inhibitor of cellular phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit á (eIF2á).

Protects cells from endoplasmic reticulum stress-induced apoptosis (EC50 ~ 15 ìM)

Chemical Formula: C21H17Cl3N4OS

Molecular Weight: 479.8

OTAVAchemicals Catalogue Number: 7119987003

CAS Registry Number: 405060-95-9

Purity: 98% (HPLC)

6-Methyl-2-((2-(naphthalen-1-yl)-2-oxoethyl)thio)pyrimidin-4(3H)-one

 I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC50=2.7 µM).

I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes. I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST.

Chemical Formula: C17H14N2O2S

Molecular Weight: 310.4

OTAVAchemicals Catalogue Number: 7110940341

CAS Registry Number: 459420-09-8

Purity: 95% (HPLC)

4-[5-(4-Chlorophenyl)-2-methyl-3-(1-oxopropyl)-1H-pyrrol-1-yl]benzenesulfonamide

Positive allosteric modulator of a7 nAChRs

Chemical Formula: C20H19ClN2O3S

Molecular Weight: 402.9

OTAVAchemicals Catalogue Number: 7070707121

CAS Registry Number: 1000279-69-5

Purity: 98% (HPLC)

2-(5-Cyano-6-oxo-4-phenyl-1,6-dihydro-pyrimidin-2-ylsulfanyl)-N-(3-trifluoromethyl-phenyl)-acetamide

Chemical Formula: C20H13F3N4O2S

Molecular Weight: 430.4

OTAVAchemicals Catalogue Number: 7020160376

CAS Registry Number: N/A

Purity: 95% (HPLC)

 (E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide

Potent, selective necroptosis inhibitor (IC50 = 0.2 µM). MLKL blocker. Selectively blocks necrosis downstream of RIP3 activation. Shows selective antinecrotic effects

Chemical Formula: C18H15N5O6S2

Molecular Weight: 461.5

OTAVAchemicals Catalogue Number: 7012180041

CAS Registry Number: 432531-71-0

Purity: 90%+ (HPLC)

Cyclohexyl-[4-(1-piperazin-1-yl[2,6]naphthyridin-3-yl)pyridin2-yl]amine

inhibitor PKD kinase

Chemical Formula: C23H28N6

Molecular Weight: 388.5

OTAVAchemicals Catalogue Number: 11639280

CAS Registry Number:1071135-06-2

Purity: 97% (HPLC)

3-Amino-5-(4-benzylphenyl)thieno[2,3-d]pyrimidin-4-one, 3-Amino-5-[4-(phenylmethyl)phenyl]thieno[2,3-d]pyrimidin-4(3H)-one (Barbadin)

selective ß-arrestin/ß2-adaptin inhibitor

Chemical Formula: C19H15N3OS

Molecular Weight: 333.4

OTAVAchemicals Catalogue Number: 0129720278

CAS Registry Number: 356568-70-2

Purity: 97% (HPLC)

1-Piperidine Cyclohexane Carbonitrile

 1-Piperidine Cyclohexane Carbonitrile  has been found as a contaminant in PCP preparations 

Chemical Formula: C12H20N2

Molecular Weight: 192.3

OTAVAchemicals Catalogue Number: 0111070275

CAS Registry Number: 3867-15-0

Purity: 95% (HPLC)

 4-[(1E)-{2-[(9E)-9H-fluoren-9-ylidene]hydrazin-1-ylidene}methyl]benzoic acid

Molecular Weight: 326.3579

OTAVAchemicals Catalogue Number: 3463893

CAS Registry Number: 904229-76-1

Purity: 95% (HPLC)

N-1-cyclohexyl-N-2-[(1-methyl-2-oxo-2,3-dihydro-1H-indol-5-yl)sulfonyl]glycinamide

Molecular Weight: 365.4546

OTAVAchemicals Catalogue Number: 1458183

CAS Registry Number: 1216772-20-1

Purity: 95% (HPLC)

5-Bromo-3,3-dimethyl-1,3-dihydro-indol-2-one

Chemical Formula: C10H10BrNO

Molecular Weight: 240.1

OTAVAchemicals Catalogue Number: 1394993

CAS Registry Number: 120902-45-6

Purity: 97% (HPLC)

8-hydroxyquinoline-5-carboxylic acid

IOX1 has an IC50 value as 200nM. IOX1 might be used in the treatment of ß-thalassemia by a-globin downregulation

Chemical Formula: C10H7NO3

Molecular Weight: 189.2

OTAVAchemicals Catalogue Number: 3476873

CAS Registry Number: 5852-78-8

Purity: 96%+ (HPLC)

(E)-2-(2-Chlorobenzylidene)hydrazinecarboximidamide; 2-[(2-Chlorophenyl)methylene]hydrazinecarboximidamide

Sephin 1 is a selective inhibitor of holophosphatase, a regulatory subunit of protein phosphatase 1

Chemical Formula: C8H9ClN4

Molecular Weight: 196.6

OTAVAchemicals Catalogue Number: 0114360035

CAS Registry Number: 13098-73-2

Purity: 95%+ (HPLC)

(5Z)-5-[(4-chlorophenyl)methylene]thiazolidine-2,4-dione

Potent inhibitor of PIM-1 with IC₅₀ values of 0.04±0.03 µM. The inhibition of PC3 prostate carcinoma cells proliferation by 21a is 49±8 µM.

Potent inhibitor of PIM-2 with IC₅₀ values of 0.2±0.1 µM. The inhibition of PC3 prostate carcinoma cells proliferation is 49±8 µM.

OTAVAchemicals Catalogue Number:   0123300047

CAS Registry Number: N/A

Purity: 100%

2-Hydroxy-4-[[[[(4-methylphenyl)sulfonyl]oxy]acetyl]amino]-benzoic acid

an inhibitor of STAT3 with anti-tumor activity; NSC 74859 in inhibition of STAT3 dimerization assays demonstrated an IC50 = 100 µM

OTAVAchemicals Catalogue Number: 7070707021

CAS Registry Number: 501919-59-1

Purity: 98% (HPLC)

1-benzyl-3-hexadecyl-2-methyl-imidazol-1-ium iodide

Human elongation factor 2 kinase (eEF-2K) inhibitor, IC50 = 60 nM

**Tautomeric double bonds in the structure **

OTAVAchemicals Catalogue Number: 7070707012

CAS Registry Number: 278603-08-0

Purity: 97%+ (CHN analysis, 13C NMR & 1H NMR)