Research Collaboration
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Research Collaboration
  • 2017-2018, our antibacterial library of compounds is investigated in collaboration with the University of Massachusetts Lowell (USA).
  • 2017-2018, in collaboration with the University of Ontario Institute of Technology (Canada), we are working on the development of a novel technology for in vitro evaluation of RNA/DNA-targeted compounds.
  • 2017-2018, in collaboration with Howard University (USA), we are studing compounds from our dopamine agonist and GPCR agonist general libraries.
  • 2016-2017, in cooperation with Monash University (Australia) we worked on the identification of novel Dengue virus replication inhibitors.
  • 2014-2016, in-vivo screening of new chemical entities targeting the nuclear receptor protein family were done in collaboration with InDanio (Canada).
  • 2013 - 2014, in cooperation with Queen's University (Canada) we have investigated in vitro activation of heme oxygenase-2 by menadione and its analogs.
  • 2012 - 2013, in collaboration with St. John's University (USA) we have developed the novel PARP-1 inhibitors.
  • 2011 - 2012, new HCV NS5B polymerase Inhibitors were discovered in collaboration with St. John's University (USA), UMDNJ-New Jersey Medical School (USA) and Kaohsiung Medical University (Republic of China).
  • 2011 - 2012, indole/quinolone derivatives were investigated as potential protein kinase CK2 inhibitors in collaboration with University of Toronto at Scarborough (Canada).
  • 2010 - 2012, in cooperation with Institute of Biochemistry University of Cologne (Germany) we have started a co-crystallization experiments to investigate molecular complexes of human kinases and ATP-competitive inhibitors.
  • 2009, in terms of joint research project with Ophthalmology Research Laboratories Cedars-Sinai Medical Center (USA) we are studying the effects of protein kinase inhibitors on cell shape and cytoskeleton in human cultured astrocytes and vascular endothelial cells.
  • 2008, in collaboration with Institute of Genetics and Molecular Medicine at University of Edinburgh (Scotland) we have focused on a protein kinase inhibitors development to obtain compounds with anti-proliferative effects.
  • 2004 - 2006, a several contract research projects were carried out in collaboration with Princeton BioMolecular Research, Inc. (USA). The projecs were dealt with virtual screening and structural modeling of protein kinases CDK2, PKC, AKT1.