Ion Channel Targeted Libraries
     
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Ion Channel Targeted Libraries

Ion channel focused libraries

To date, ion channel modulators have been identified by various means, relatively few of which have so far been focused on direct screening of compounds for their activity on the channel(s) of interest. The past few years have seen significant developments that facilitate the identification of novel ion channel modulators. These improvements in screening methods should lead to more selective agents being identified and progressing into clinical development.

 

 
For the moment, OTAVAchemicals offers Ion Channel Targeted Libraries designed with Ligand-based approach. These libraries are proposed for screening in ion channel-associated research and drug development projects.

  • the libraries contain drug-like compounds only
  • all the compounds are in stock
  • cherry picking is available

 

 

Name Number of compounds Approach Details
GABAA agonist library 396 Ligand-based read more
GABAA antagonist library 543 Ligand-based read more
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker library 657 Ligand-based read more
Calcium channel blocker library 1008 Ligand-based read more
Sodium channel blocker library 658 Ligand-based -
Voltage-gated sodium channel blocker library 1477 Ligand-based read more
Kv1.5 potassium channel blocker library 940 Ligand-based read more

OTAVAchemicals Targeted Libraries Collection
Name Number
Kinases 69
Proteases 17
GPCRs 51
Ion channels 5
Disease-based libraries 74
Epigenetic targets 8
Protein-Protein Interaction 2
Peptidomimetic 2
Nuclear Receptors 12
Glycomimetic 1
RNA binding 1
SH2 binding 1
General Activities 128
Other 93

 

 

The libraries (SDF, XLS, PDF format) are available on request. Feel free to contact us or use on-line form below to send an inquiry if you are interested to obtain these libraries or if you need more information.

 

 

 

 

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