EGFR-kinase inhibitor
     
Home > PRODUCTS > Biochemicals > EGFR-kinase inhibitor

Newsletter Subscription

Stay updated with our new products and services. You can unsubscribe at any time.


EGFR-kinase inhibitor

N-(3-Bromophenyl)-6,7-dimethoxy-4-quinazolinamine hydrochloride

Inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase IC50 = 29 pM 

EGFR-kinase_inhibitor
OTAVAchemicals Catalogue Number: 7020540711
CAS Registry Number: 153436-54-5

Purity: 95%+ (HPLC)


Ref.: Science 1994, 265, 5175, 1093 – 1095


Abstract: PD 153035 rapidly suppressed autophosphorylation of the EGF receptor at low nanomolar concentrations in fibroblasts or in human epidermoid carcinoma cells and selectively blocked EGF-mediated cellular processes including mitogenesis, early gene expression, and oncogenic transformation. 

DOI: 10.1126/science.8066447

 


Price info:
1 MG 20 EUR
5 MG 50 EUR
10 MG 70 EUR
300uL of 10mM solution

40 EUR

 

 

 
 
SSL