EGFR-kinase inhibitor
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EGFR-kinase inhibitor

N-(3-Bromophenyl)-6,7-dimethoxy-4-quinazolinamine hydrochloride

Inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase IC50 = 29 pM 

OTAVAchemicals Catalogue Number: 7020540711
CAS Registry Number: 153436-54-5

Purity: 95%+ (HPLC)

Ref.: Science 1994, 265, 5175, 1093 – 1095

Abstract: PD 153035 rapidly suppressed autophosphorylation of the EGF receptor at low nanomolar concentrations in fibroblasts or in human epidermoid carcinoma cells and selectively blocked EGF-mediated cellular processes including mitogenesis, early gene expression, and oncogenic transformation. 

DOI: 10.1126/science.8066447


Price info:
1 MG 20 EUR
5 MG 50 EUR
10 MG 70 EUR
300uL of 10mM solution

40 EUR