HDAC1 & 2 Inhibitor
     
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HDAC1 & 2 Inhibitor

4-acetamido-N-[2-amino-5-(2-thienyl)phenyl]benzamide

Histone deacetylase HDAC1/2 selective inhibitor, HDAC1 IC50 = 0.007 µM, HDAC2 IC50 = 0.049 µM,

HCT116 proliferation assay GI50 = 0.11 µM 

HDAC1_2_Inhibitor

OTAVAchemicals Catalogue Number: 7070707091
CAS Registry Number: 849234-64-6

Purity: 97%

 

Ref.:  Bioorg. Med. Chem. Lett. 2008, 18, 973–978


Abstract: Selective HDAC1/2 inhibitor, exhibiting selectivity over class II HDACs 3–8. Histone deacetylases are considered promising targets for cancer epigenetic therapy. Elimination of HIV-1 latently infected cells by gnidimacrin - a protein kinase C (PKC) agonist was potentiated by TPB in cell models by 2–3 folds

DOI: 10.1016/j.bmcl.2007.12.031

 


Price info:
1 MG 80 EUR
5 MG 170 EUR
10 MG 240 EUR
300uL of 10mM solution

120 EUR

 

 
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