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Wnt/ß-catenin pathway inhibitor


Chemical Formula: C21H18ClN3

Molecular Weight: 347.9

OTAVAchemicals Catalogue Number:  0117890066

CAS Registry Number:  305372-78-5

Purity:  98%


Ref.: Cancer Res. 2010, 70, 14, 5963–5973.

Abstract:  CCT036477 demonstrated activity against several cancer cell lines (HT29, HCT116, SW480 with GI50 17.7 - 33.3 µM), blocked development of Zebrafish and Xenopus laevis embryos at 20 µmol/L and reduced expression of two well-characterized Wnt target genes (Siamois and Xnr3) in animal cap assays

DOI: 10.1158/0008-5472.CAN-10-1028


Price info:
1 MG 20 EUR
5 MG 70 EUR
10 MG 100 EUR
300uL of 10mM solution

50 EUR