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autophagy inhibitor


Chemical Formula: C15H11F2N3

Molecular Weight: 271.3

OTAVAchemicals Catalogue Number:  1736860

CAS Registry Number:  1262888-28-7

Purity:  95%


Ref.: Cell 2011, 147, 1, 223-234

Abstract: Spautin-1 is a specific and potent autophagy inhibitor and enhancer of apoptosis. It promotes the degradation of Vps34 PI3 kinase complexes by inhibiting two ubiquitin-specific peptidases, USP10 and USP13,with IC50 ~0.6-0.7 µM.

DOI: 10.1016/j.cell.2011.08.037


Price info:
1 MG 20 EUR
5 MG 50 EUR
10 MG 70  EUR
300uL of 10mM solution

35 EUR