N,4-dimethyl-5-[2-(3-methylsulfonylanilino)pyrimidin-4-yl]thiazol-2-amine

Selective CDK2 and CDK9 inhibitor

Chemical Formula: C16H17N5O2S2

Molecular Weight: 375.5

OTAVAchemicals Catalogue Number:  3485491

CAS Registry Number:  870780-40-8

Purity:  95%

Ref.: Chemistry & Biology 2010, 17, 1111–1121

Abstract:  CAS# 870780-40-8 inhibits a family of cyclin-dependent kinases (CDKs) which are key cell cycle regulators and some of them also have regulatory functions in mRNA transcription. Selectively inhibited CDK2 and CDK9 with Ki 1.6nM and 0.29nM, respectively

DOI: 10.1016/j.chembiol.2010.07.016

Need more information regarding this product? Send us an inquiry: Name: * First Last Company: * E-mail: (if you do not receive a response within 24 hours, please check your email spam folder, as it may have been blocked by your spam filter) * Please specify name of the product: * Word Verification: type_submit_reset_7 SubmitReset