7070707016

Newsletter Subscription

Stay updated with our new products and services. You can unsubscribe at any time.


7070707016

Histone_Deacetylase_Inhibitor_VI

N-Hydroxy-7-(2-naphthalenylthio)-heptanamide

HNHA is a cell-permeable inhibitor of histone deacetylase (HDAC) activity (IC50 = 100 nM)

OTAVAchemicals Catalogue Number: 7070707016

CAS Registry Number: 926908-04-5

Purity: 98% (HPLC)

 


Ref.: Kim et al. Anti-tumor activity of N-hydroxy-7-(2-naphthylthio)heptanomide, a novel histone deacetylase inhibitor. Biochemical and Biophysical Research Communications (2007), 356, 233-238


Abstract: A cell-permeable hydroxyamide-based SAHA analog that potently inhibits histone deacetylase (HDAC) activity (IC50 = 100 nM). Shown to induce histone acetylation and p21 transcription with concomitent inhibition of cell cycle progression in human fibrosarcoma HT1080 cells. Reported to be more potent than SAHA in inhibiting tumor growth in a murine xenograph model in vivo.

DOI: 10.1016/j.bbrc.2007.02.126

Price info:
1 MG 39 EUR
5 MG 79 EUR
10 MG 99 EUR
300uL of 10mM solution 59 EUR

 

Need more information regarding this product? Send us an inquiry:


Name: *
Company: *


E-mail:
(if you do not receive a response within 24 hours,

please check your email spam folder,

as it may have been blocked by your spam filter)
*

Please specify name of the product:
*
Word Verification:

 
SSL