Kinesin-like protein 1 Inhibitor
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Kinesin-like protein 1 Inhibitor


Potent inhibitor of Kinesin-like protein 1 with activity in the ATPase assay of 1.7±0.4 μM and the MPM-2 cytoblot assay of 0.48±0.13 μM.


OTAVAchemicals Catalogue Number:   7112880116

CAS Registry Number: 301321-93-7

Purity: 95%+


Ref.: A. B. Pinkerton et al. Synthesis and SAR of thiophene containing kinesin spindle protein  (KSP) inhibitors. Bioorg. Med. Chem. Lett. 17 (2007) 3562–3569.

Abstract: We have identified and synthesized a series of thiophene containing inhibitors of kinesin spindle protein. SAR studies led to the synthesis of 33, which was co-crystallized with KSP and determined to bind to an allosteric pocket previously described for other known KSP inhibitors.


Price info:
1 MG 30 EUR
5 MG 40 EUR
10 MG 50 EUR
300uL of 10mM solution

40 EUR