7070707143

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7070707143

Dual VEGFR-2 and tubulin inhibitor

(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-(5-{2-[(pyridin-4-ylmethyl)-amino]-phenyl}-[1,3,4]oxadiazol-2-yl)-amine

 Tubulin polymerization inhibitor ITP IC50 =  1.09 µM, G2/M transition block EC50 = 0.009 µM,

VEFGR-2 enzyme IC50 = 0.21 µM, VEGFR-2 cell IC50 = 0.11 µM

OTAVAchemicals Catalogue Number:  7070707143

CAS Registry Number:  830333-53-4

Purity:  95%+

 

 

 

Ref.: ACS Med. Chem. Lett. 2010, 1, 488–492

Abstract: Dual VEGFR-2 kinase and tubulin polymerization inhibitor allowing inhibition of both tumor cells and tumor vasculature

DOI: 10.1021/ml1001568

 


Price info:
1 MG 20 EUR
5 MG 70 EUR
10 MG 100 EUR
300uL of 10mM solution

50 EUR

 

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