4-[[2-[(1-benzylindol-5-yl)amino]-6-(ethylamino)pyrimidin-4-yl]amino]cyclohexanol

Cyclin-dependent kinase 4/6 specific inhibitor, Cdk4/cyclin D1 IC50 = 1.5 µM, Cdk6/cyclin D1 IC50 = 5.6 µM

OTAVAchemicals Catalogue Number: 1112092

CAS Registry Number: 359886-84-3

Purity: 98% (HPLC)

Ref.: J. Nat. Canc. Inst. 2001, 93, 6, 436-446

Abstract: CINK4 specifically inhibits Cdk4/cyclin D1 and Cdk6/cyclin D1 activity in vitro and slows tumor growth in vivo.

DOI: 10.1093/jnci/93.6.436

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