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Fragment-based lead design (FBLD) could be used to identify new metal-binding groups for metalloenzyme inhibitors. Several small-molecule chelators have been shown to effectively inhibit metalloproteins, therefore the design,
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The Targeted AHR Modulator Library is a curated chemical screening set designed to accelerate the discovery of novel small-molecule modulators of the aryl hydrocarbon receptor (AHR) — a ligand-dependent transcription factor with key roles in immunity, cancer, inflammation, and xenobiotic metabolism.
This unique compound library supports early-stage discovery, target validation, and therapeutic innovation by providing access to structurally diverse and computationally prioritized molecules tailored for AHR-centric research and drug development programs.
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